1 00:00:01,605 --> 00:00:05,106 So you're probably feeling pretty comfortable with the diagram of the heart, 2 00:00:05,106 --> 00:00:08,705 but let me just go ahead and label a few things, just to make sure we're all on the same page. 3 00:00:08,705 --> 00:00:11,603 Blood flows from the right atrium to the right ventricle, 4 00:00:11,603 --> 00:00:16,136 then it goes to the lungs and from the left atrium to the left ventricle. 5 00:00:16,136 --> 00:00:19,343 That's usually the flow of blood. 6 00:00:19,343 --> 00:00:24,269 One of the things that keeps the blood flowing in the right direction is the valves. 7 00:00:24,269 --> 00:00:28,100 Two of the valves I'm gonna name, I'm giving them new names, 8 00:00:28,100 --> 00:00:31,837 something slightly different from what we've been referring to them by. 9 00:00:31,837 --> 00:00:35,038 These are the atrioventricular valves. 10 00:00:35,038 --> 00:00:38,917 You can take a guess as to which ones I'm referring to. 11 00:00:38,917 --> 00:00:45,204 Atrioventricular valves are the two valves between the atria and the ventricles. 12 00:00:45,204 --> 00:00:50,137 One will be the tricuspid valve and the other the mitral valve. 13 00:00:50,137 --> 00:00:57,035 Just to orientate us: this is the tricuspid (T) and this is our mitral (M). 14 00:00:57,035 --> 00:01:02,534 The atrioventricular valves, if you look at them, they're both kind of facing downwards. 15 00:01:02,534 --> 00:01:08,437 One of the things you might be wondering is 'How is it that they aren't just flopping back and forth?' 16 00:01:08,437 --> 00:01:12,209 These valves in particular have a very interesting strategy, 17 00:01:12,209 --> 00:01:18,703 they're actually tethered to the walls. 18 00:01:18,703 --> 00:01:25,072 They're held down here, like that. 19 00:01:25,072 --> 00:01:31,135 They have on the other end of those tethers a little muscle. 20 00:01:31,135 --> 00:01:34,048 This makes perfect sense if you think about it. 21 00:01:34,048 --> 00:01:40,003 The ventricles are very strong, right? We know the ventricles are really really strong. 22 00:01:40,003 --> 00:01:47,874 If the ventricles are squeezing, there's a good chance the blood is gonna shoot up in any direction it can go. 23 00:01:47,874 --> 00:01:58,537 It's gonna go back perhaps through the mitral valve, it can go there, or it might go through the tricuspid valve. 24 00:01:58,537 --> 00:02:06,569 The reason that it won't, is that these papillary muscles are basically sending out little life lines, these chordae tendinae, 25 00:02:06,569 --> 00:02:10,770 to keep the valve from flipping backwards. 26 00:02:10,770 --> 00:02:17,003 So these chordae tendinae, these cords are important for that reason. 27 00:02:17,003 --> 00:02:21,749 They keep the valve from flipping backwards. 28 00:02:21,749 --> 00:02:26,835 These are all the chordae tendinae and these are the papillary muscles. 29 00:02:26,835 --> 00:02:36,379 These are particularly important for when you're trying to make sure that ventricles don't screw up the valves. 30 00:02:36,379 --> 00:02:44,436 Let's say that by accident our ventricle was just too strong, too powerful, let's say it broke one of these cords. 31 00:02:44,436 --> 00:02:46,500 Let's say it broke this one right here. 32 00:02:46,500 --> 00:02:52,813 That's because our ventricle was just forcing too much blood back and it just snapped the cord. 33 00:02:52,813 --> 00:02:54,140 What would happen? 34 00:02:54,140 --> 00:03:01,752 This would basically start flipping back and forth, it would flip this way and this way. 35 00:03:01,752 --> 00:03:05,671 On the next heartbeat, blood would start going the wrong direction, 36 00:03:05,671 --> 00:03:10,074 because this valve is not able to maintain a nice tight seal. 37 00:03:10,074 --> 00:03:15,270 Blood would basically go this way when it wasn't supposed to. 38 00:03:15,270 --> 00:03:19,877 All of a sudden our flow of blood is going in the wrong direction. 39 00:03:19,877 --> 00:03:25,934 The chordae tendinae and the papillary muscles do a really important job in preventing that from happening. 40 00:03:25,934 --> 00:03:28,587 Let's move our attention to another area. 41 00:03:28,587 --> 00:03:38,104 Let's focus on this right here, which is the interventricular septum. 42 00:03:38,104 --> 00:03:40,438 You can think of a septum as a wall. 43 00:03:40,438 --> 00:03:43,269 Interventricular septum. 44 00:03:43,269 --> 00:03:48,275 This interventricular septum, the one thing I want to point out, which is maybe fairly obvious, 45 00:03:48,275 --> 00:03:51,834 when you look at it, you might think, you didn't have to say it, it's pretty obvious, 46 00:03:51,834 --> 00:03:57,704 this area is really thin and this area is really thick by comparison, right? 47 00:03:57,704 --> 00:04:02,034 The two areas are not equal in size, this is much thicker. 48 00:04:02,034 --> 00:04:08,612 The reason I bring that up is because the first area, in blue, is called the membranous part. 49 00:04:08,612 --> 00:04:11,969 It's literally like a membrane. 50 00:04:11,969 --> 00:04:17,336 The bottom, the red part, is the muscular part. This is the strong muscular part. 51 00:04:17,336 --> 00:04:22,413 You have two different areas in that interventricular septum, the wall between the ventricles. 52 00:04:22,413 --> 00:04:27,076 One of the interesting things about the membranous part in particular, 53 00:04:27,076 --> 00:04:32,831 is that a lot of babies are born with holes in that membranous part. 54 00:04:32,831 --> 00:04:36,375 When I say a lot I don't mean the majority of babies by any means. 55 00:04:36,375 --> 00:04:44,036 But one of the most common defects would be that you would have a communication between these two. 56 00:04:44,036 --> 00:04:52,701 So blood would flow from the left ventricle, into a place it shouldn't be going, the right ventricle. 57 00:04:52,701 --> 00:04:56,645 Blood could flow through those holes and that is a problem. 58 00:04:56,645 --> 00:05:04,505 That is called a VSD. You might hear that term at some point, so I just wanna point out where that happens. 59 00:05:04,505 --> 00:05:11,501 While I'm writing this, you can take a guess at what this might stand for. 60 00:05:11,501 --> 00:05:20,071 Ventricular Septal (septal just means wall) Defect. 61 00:05:20,071 --> 00:05:27,600 A VSD is most common in the membranous part, more so than the muscular part. 62 00:05:27,600 --> 00:05:35,467 Let's move on again to one final thing I wanna point out, I wanna zoom in on the wall. 63 00:05:35,467 --> 00:05:42,769 Here in this grey box I'm gonna highlight what's going on in this wall, how many layers there are in this wall. 64 00:05:42,769 --> 00:05:48,676 I'm gonna draw a rectangle to correspond to the little rectangle I drew on the heart itself. 65 00:05:48,676 --> 00:05:54,503 There are 3 layers to the heart muscle. 66 00:05:54,503 --> 00:06:00,200 I'm gonna go through all three layers, we'll start on the inside and work our way out. 67 00:06:00,200 --> 00:06:04,047 On the inside you have what's called the endocardium. 68 00:06:04,047 --> 00:06:10,104 I'm gonna draw the endocardium all the way around here, it goes all the way around the valves. 69 00:06:10,104 --> 00:06:14,437 So you've already learned that the valves got endocardium. 70 00:06:14,437 --> 00:06:21,475 It goes around the ventricle and, as I showed you in the beginning, also around the atrium. 71 00:06:21,475 --> 00:06:26,942 It goes all the way up and covers both the left and right side. 72 00:06:26,942 --> 00:06:35,584 The endocardium is very similar in many ways to the inner lining of the blood vessels. 73 00:06:35,584 --> 00:06:38,269 It's a really thin layer, not a very thick layer. 74 00:06:38,269 --> 00:06:42,903 It's the layer all the red blood cells are bumping up against. 75 00:06:42,903 --> 00:06:50,734 When the red blood cells are entering the chambers of the heart, the part they're gonna see is the endocardium. 76 00:06:50,734 --> 00:06:56,082 This is what it looks like, this is that green layer all the way around that I've drawn now. 77 00:06:56,082 --> 00:07:01,255 If I was to draw a blown up version, it might look like this. 78 00:07:01,255 --> 00:07:03,171 It's a few cell layers thick. 79 00:07:03,171 --> 00:07:09,138 On the inside you have some red blood cells bumping along. 80 00:07:09,138 --> 00:07:15,770 This is one RBC,this is another one and they would bump into that endocardium. 81 00:07:15,770 --> 00:07:19,270 If you go a little bit deeper than the endocardium, what do you get to next? 82 00:07:19,270 --> 00:07:23,437 Next is the myocardium. 83 00:07:23,437 --> 00:07:30,370 That would be the biggest chunk of our wall. 84 00:07:30,370 --> 00:07:33,586 It would look something like this. 85 00:07:33,586 --> 00:07:38,745 The myocardium you can kind of see the shape, just without me pointing it out, 86 00:07:38,745 --> 00:07:42,438 because it's the most common part of this entire thing, right? 87 00:07:42,438 --> 00:07:48,336 This is our myocardium. 88 00:07:48,336 --> 00:07:54,738 Let me go back and actually label the endocardium as well. 89 00:07:54,738 --> 00:08:03,467 Just notice that these words are all pretty similar. Myo- means muscle. 90 00:08:03,467 --> 00:08:06,148 While I'm on the myocardium, let me just point out one more thing. 91 00:08:06,148 --> 00:08:10,905 The myocardium is where all of the contractile muscle is gonna be. 92 00:08:10,905 --> 00:08:12,970 That's where a lot of the work is being done. 93 00:08:12,970 --> 00:08:16,588 It's also where a lot of energy is being used up. 94 00:08:16,588 --> 00:08:23,376 When the heart needs oxygen, it's usually the myocardium, because that's the part that's doing all of the work. 95 00:08:23,376 --> 00:08:27,046 Now on the other side of the myocardium, what do we have on the outside? 96 00:08:27,046 --> 00:08:29,380 We have a layer called the pericardium. 97 00:08:29,380 --> 00:08:32,703 Let me try to draw that for you. 98 00:08:32,703 --> 00:08:34,768 The pericardium is something like this, kind of a thin layer. 99 00:08:34,768 --> 00:08:39,911 The interesting thing about pericardium is that there are actually two layers to it. 100 00:08:39,911 --> 00:08:42,369 It's actually something like this. 101 00:08:42,369 --> 00:08:50,083 Where you have two layers, an inner and an outer layer and between the two layers you literally have a gap. 102 00:08:50,083 --> 00:08:51,975 There's a gap right there. 103 00:08:51,975 --> 00:08:59,405 In that gap you might have a little bit of fluid, but it's not actually cells. 104 00:08:59,405 --> 00:09:04,213 I guess that's the biggest point, it's not cells, it's just a little bit of fluid. 105 00:09:04,213 --> 00:09:10,567 So this whole thing is called the pericardium. 106 00:09:10,567 --> 00:09:16,436 You might be wondering 'How do you get a layer that has a gap within it?' 107 00:09:16,436 --> 00:09:20,970 Let me try to show you what happens in a fetus. 108 00:09:20,970 --> 00:09:25,134 Let's say you have a little fetus heart, a tiny little heart like this. 109 00:09:25,134 --> 00:09:27,370 It gets a little bit bigger, like this. 110 00:09:27,370 --> 00:09:31,169 And finally it gets into an adult heart, something like that. 111 00:09:31,169 --> 00:09:33,249 This would be the adult heart, right? 112 00:09:33,249 --> 00:09:40,169 Well, at the same time the heart is growing, you also have a sac, almost like a balloon. 113 00:09:40,169 --> 00:09:48,503 This balloon begins to envelope the heart. 114 00:09:48,503 --> 00:09:50,968 This growing heart grows right into the balloon. 115 00:09:50,968 --> 00:09:54,635 This balloon starts going around it, like that. 116 00:09:54,635 --> 00:09:56,769 You'll get something like this. 117 00:09:56,769 --> 00:10:01,203 Eventually, as the heart gets really big, you get something like this. 118 00:10:01,203 --> 00:10:08,671 You basically have this inner layer of the balloon that's not even looking like a balloon anymore, it's very flat. 119 00:10:08,671 --> 00:10:15,217 Then it folds back on itself, like that, and it comes all the way around. 120 00:10:15,217 --> 00:10:19,984 Now you can see why even though it's continuous, I mean, it's not like it breaks, it is continuous here, 121 00:10:19,984 --> 00:10:28,619 you can see how, if you were just looking at at chunk of it, like we're looking at right here, 122 00:10:28,619 --> 00:10:32,185 you can see how it would look like a pancake. 123 00:10:32,185 --> 00:10:38,685 On our heart it literally would be something like this, a very thin kind of pancake. 124 00:10:38,685 --> 00:10:44,122 I'm not doing a very good job making it look thin, but you can imagine what it is, 125 00:10:44,122 --> 00:10:47,817 what it could look like if I was to zoom in on it, basically something like that. 126 00:10:47,817 --> 00:10:56,257 You have two layers that are just turned in on themselves. Both layers together are called the pericardium. 127 00:10:56,257 --> 00:10:59,618 There are actually separate names for the two layers. 128 00:10:59,618 --> 00:11:05,181 For example, the layer that's kind of hugging up against the heart, this layer that I'm drawing now, 129 00:11:05,181 --> 00:11:09,250 this layer is called the visceral pericardium. 130 00:11:09,250 --> 00:11:11,420 So you call that the visceral pericardium. 131 00:11:11,420 --> 00:11:21,616 The name visceral, this right here would be visceral, the reason it's called visceral is because viscera means organs. 132 00:11:21,616 --> 00:11:24,517 So that's called the visceral pericardium. 133 00:11:24,517 --> 00:11:31,585 This outer layer, the one I'm drawing now, is called the parietal pericardium. 134 00:11:31,585 --> 00:11:35,683 That's the layer on the outside. 135 00:11:35,683 --> 00:11:41,918 Let me label that as well as this guy, that would be the parietal pericardium. 136 00:11:41,918 --> 00:11:47,568 Now you can actually see the layers of the heart, the endocardium, myocardium and pericardium. 137 00:11:47,568 --> 00:11:52,816 And to throw you a curveball, as I'm pretty sure you can handle it, 138 00:11:52,816 --> 00:12:00,582 this visceral pericardium, another name for it, because you might see it sometime, is the epicardium. 139 00:12:00,582 --> 00:12:02,893 Sometimes you might see it, the epicardium. 140 00:12:02,893 --> 00:12:06,718 Don't get thrown of, it's really just the visceral pericardium. 141 00:12:06,718 --> 00:12:10,718 It's just the outermost layer of the heart before you get to the parietal pericardium.